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Tramadol Highlights

  • Tramadol oral medicine is available as a generic and brand name tablet under different names.
  • The most common brand name for oral tramadol tablets is Ultram and Ultram ER (extended-release version)
  • Oral tablets of tramadol are accessible as immediate delivery and extended delivery medications (capsules)
  • The medication is useful to treat moderate to moderately severe pain.

What is tramadol?

Tramadol is opioid pain-relieving medication use to treat acute and chronic moderate to severe pain. When you take tramadol oral immediate-release tablets, the onset of pain relief generally begins within an hour. The medication is also available as an injection for veins and muscles. Many pharmaceutical companies also sell tramadol combined with other medicines such as paracetamol (acetaminophen/tramadol).

Tramadol drug class is opioid analgesics. It works in the brain to accelerate opioid receptors, thus causing pain relief.

The medication is a scheduled substance. Tramadol schedule is IV under the Controlled Substance Act by the Drug Enforcement Administration.

What is tramadol used for?

The primary tramadol uses are to relieve and manage pain caused due to different medical conditions. It treats both acute and chronic pain. However, the extended-release tramadol is generally prescribed for chronic pain conditions that require around-the-clock pain-relieving medications.

A doctor may prescribe tramadol as a single medication or in combination with other medicines. Some people also buy tramadol online to use it as a treatment option for fibromyalgia. However, this use of the medication is not FDA-approved. The NHS approved the use of tramadol as a second-line medication as a painkiller for fibromyalgia.

The analgesic effects of tramadol take about an hour to come into effect and approximately 2 to 4 hours to reach the peak concentration with an immediate delivery formulation.

Comparing on a dose by dose basis, tramadol has one-tenth potency as morphine and is practically equally as potent as codeine and pethidine.

How does tramadol work?

Doctors prescribe tramadol for pain. It is an opioid agonist member of the opioid class. It works by altering the way the brain senses pain. Tramadol is similar to some brain substances called endorphins. The endorphins attach to the brain receptors to reduce the pain messages sent by the body to the brain. The medication works in a similar way to reduce the degree of pain that the brain thinks a person has.

The medication induces analgesic effects through various targets on the serotonin system, noradrenergic system, and opioid receptor system. Tramadol HCL exists as a racemic mixture that inhibits the serotonin reuptake. It also acts as a serotonin releasing agent.

What are the side effects of Tramadol?

Tramadol pills generally cause drowsiness. People are advised not to drive, use hefty machinery, or do any task requiring mental alertness when they are on the medication. The medicine may also cause other unwanted effects. The most frequently occurring tramadol side effects include:

  • Headache
  • Dizziness
  • Drowsiness
  • Sweating
  • Lack of energy
  • Constipation
  • Dry mouth
  • Nausea and vomiting

These effects are usually mild, and they subside with the continued use of the medication for a couple of days or a week.

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