The High Energy Chemistry / Hazardous Chemistry- based API manufacturing services market is projected to grow at an annualized rate of ~8%, till 2030
Roots Analysis has done a detailed study on High Energy Chemistry / Hazardous Chemistry-based API Manufacturing Services Market: Focus on High Temperature, Low Temperature / Cryogenic, High Pressure and Low Pressure Chemistries, 2020-2030, covering key aspects of the industry’s evolution and identifying potential future growth opportunities.
Key Market Insights
- Presently, over 100 service providers across the globe have capabilities to handle high energy / hazardous chemistry conditions, offering contract and custom manufacturing services for pharmaceutical APIs
- The market landscape is highly fragmented, featuring the presence of both established players and new entrants; majority of the companies have presence in Europe and Asia Pacific regions
- API manufacturing facilities of service providers are well equipped to handle / maintain a wide range of temperature and pressure conditions to carry out HEC reactions
- Industry stakeholders are actively expanding their existing capabilities through installation of advanced equipment at their manufacturing facilities, in order to maintain a competitive edge in the market
- Service Providers are offering a diverse portfolio of reactions for manufacturing of synthetic APIs; Hydrogenation and Grignard reactions are the most popular types of reactions offered by players
- Case In Point: Contract research service providers cater to the needs related to process development and small scale synthesis of APIs based on HEC / hazardous chemistry
- In the long-term, the projected opportunity is anticipated to be worth USD 29 billion by 2030; the opportunity is anticipated to be well distributed across companies of varying sizes, scale of operation and geographies
Table of Contents
- PREFACE
- Scope of the Report
- Research Methodology
- Chapter Outlines
- EXECUTIVE SUMMARY
- INTRODUCTION
- Chapter Overview
- Overview of High Energy Chemistry (HEC) / Hazardous Chemistry for Small Molecule API Manufacturing
- Low Temperature / Cryogenic Chemistry
- Reaction Conditions
- Advantages
- Affiliated Production Processes
- Other Specific Requirements / Equipment
- List of Reactions
- High Temperature Chemistry
- Reaction Conditions
- Advantages
- Affiliated Production Processes
- Other Specific Requirements / Equipment
- List of Reactions
- High Pressure Chemistry
- Reaction Conditions
- Advantages
- Affiliated Production Processes
- Other Specific Requirements / Equipment
- List of Reactions
- Need for Outsourcing HEC / Hazardous Chemistry-Based API Manufacturing in the Pharmaceutical Industry
- Shift Towards Continuous Flow Chemistry
- CASE STUDY: COMPARISON OF SMALL MOLECULES AND LARGE MOLECULES
- Chapter Overview
- Small Molecule and Large Molecule Drugs / Therapies
- Comparison of Key Characteristics
- Comparison of Manufacturing Processes
- Comparison of Key Manufacturing-related Challenges
4.3 HEC / Hazardous Chemistry for Small Molecule Manufacturing
- CURRENT MARKET LANDSCAPE
- Chapter Overview
- API Manufacturers with HEC Capability: Overall Market Landscape
- Analysis by Type of Manufacturing Service
- Analysis by Year of Establishment
- Analysis by Company Size
- Analysis by Geographical Location
- Analysis by Location of Manufacturing Facilities
- Analysis by General Pharmaceutical Manufacturing Portfolio
- Analysis by Type of Product (API and FDF)
- Analysis by HPAPI Manufacturing Capability
- Analysis by Type of HEC Services Offered
- Analysis by Temperature Conditions Handled
- Analysis by Pressure Conditions Handled
- Analysis by Availability of Continuous Flow Technology
- REGIONAL CAPABILITY ASSESSMENT
- Chapter Overview
- List of Manufacturing Facilities having HEC Capabilities
- Manufacturing Facilities in North America
- Geographical Map Representation: Manufacturing Facilities with HEC Capabilities in North America
- Analysis by Type of Reaction Conditions Handled
- Analysis by Range of Reaction Conditions Handled
- Analysis by Temperature Conditions Handled
- Analysis by Pressure Conditions Handled
- Manufacturing Facilities in Europe
- Geographical Map Representation: Manufacturing Facilities with HEC Capabilities in Europe
- Analysis by Type of Reaction Conditions Handled
- Analysis by Range of Reaction Conditions Handled
- Analysis by Temperature Conditions Handled
- Analysis by Pressure Conditions Handled
- Manufacturing Facilities in Asia Pacific
- Geographical Map Representation: Manufacturing Facilities with HEC Capabilities in Asia Pacific
- Analysis by Type of Reaction Conditions Handled
- Analysis by Range of Reaction Conditions Handled
- Analysis by Temperature Conditions Handled
- Analysis by Pressure Conditions Handled
- Manufacturing Facilities in North America
- Regional Capability Assessment Summary
- COMPANY COMPETITIVENESS ANALYSIS
- Chapter Overview
- Key Parameters
- Methodology
- Competitiveness Analysis: Companies in North America
- Companies in North America Offering HEC-based Contract Manufacturing
- Companies in North America Offering HEC-based Custom Manufacturing
- Competitiveness Analysis: Companies in Europe
- Companies in Europe Offering HEC-based Contract Manufacturing
- Companies in Europe Offering HEC-based Custom Manufacturing
- Competitiveness Analysis: Companies in Asia Pacific
- Companies in Asia Pacific Offering HEC-based Contract Manufacturing
- Companies in Asia Pacific HEC-based Offering Custom Manufacturing
- Spider Web Analysis
- COMPANY PROFILES
- Chapter Overview
- AGC Chemicals
- Company Overview
- Financial Information
- Manufacturing Facility Details
- HEC Specific Service Offerings
- Recent Developments and Future Outlook
- Beijing Mediking Biopharm
8.3.1 Company Overview
8.3.2 Manufacturing Facility Details
8.3.3 HEC Specific Service Offerings
8.3.4. Recent Developments and Future Outlook
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- Cambrex
- Company Overview
- Financial Information
- Manufacturing Facility Details
- HEC Specific Service Offerings
- Recent Developments and Future Outlook
- Corden Pharma
- Cambrex
8.5.1 Company Overview
8.5.2 Manufacturing Facility Details
8.5.3 HEC Specific Service Offerings
8.5.4 Recent Developments and Future Outlook
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- Evonik
- Company Overview
- Financial Information
- Manufacturing Facility Details
- HEC Specific Service Offerings
- Recent Developments and Future Outlook
- Hovione
- Company Overview
- Manufacturing Facility Details
- HEC Specific Service Offerings
- Recent Developments and Future Outlook
- Patheon
- Company Overview
- Manufacturing Facility Details
- HEC Specific Service Offerings
- Recent Developments and Future Outlook
- PCI Synthesis
- Company Overview
- Manufacturing Facility Details
- HEC Specific Service Offerings
- Recent Developments and Future Outlook
- Siegfried
- Company Overview
- Manufacturing Facility Details
- HEC Specific Service Offerings
- Financial Information
- Recent Developments and Future Outlook
- Evonik
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