Sildenafil citrate is being marketed under the brand name Viagra. Pill, which deals with pulmonary and present arterial hypertension. It is also known for treating sexual dysfunction in men.
Viagra pill
Sildenafil citrate is being marketed under the brand name Viagra. Pill, which deals with pulmonary and present arterial hypertension. It is also known for treating sexual dysfunction in men.
It comes in tablet form, which is being taken by mouth. T also comes in injection form, which needs to be injected in measure. It shows its effects within 20 minutes and reaches its peak time in about 2 hours.
Viagra – its uses
Sexual Dysfunction
It is being used in the treatment of erectile dysfunction. It is explained as unable to maintain a satisfactory erection to complete sexual intercourse.
Antidepressant-associated sexual dysfunction
It is being used as an antidepressant. Those experience depression caused by erectile dysfunction.
Raynaud’s phenomenon
Sildenafil citrate or viagra pill is being used as off-label in order to relieve vasospasm, severe ischemia. It also includes soreness in the fingers and toes in people with Raynaud’s phenomenon.
The drugs mentioned above reduce the frequency and duration of vasospastic episodes.
High-altitude pulmonary edema
Viagra pill is being found useful in high-altitude pulmonary edema. Due to some reasons, currently, it is not recommended.
Side effects of Viagra
The most common Sildenafil side effects are headache, flushing, and indigestion, including nasal congestion and impaired or blurred vision.
In some cases, it is also seen that there is deafness also as a side effect of the viagra pill. In October 2007, the FDA directed all the pharmaceutical companies to mention deafness as it has a severe side effect.
Effects on Liver
In a new study, scientists have determined that Sildenafil, under the brand name Viagra, is known to treat erectile dysfunction (male impotence) and pulmonary arterial hypertension (PAH), does not affect blood flow in a sufferer with cirrhosis.
Effects on Kidney
In conclusion, the use of sildenafil citrate in patients with pre-existing kidney disease should take special care, especially in the case of overdose, which can lead to devastating complications. The likelihood of ATN can be even higher if taken with nitrates.
Long Term Side Effects
The use of the Viagra pill does not cause new or worsening erectile dysfunction. Still, the Viagra pills can sometimes cause priapism. That might be a long-lasting and sometimes painful erection.
Priapism is a medical emergency that requires treatment immediately. If left untreated, priapism can damage the tissues of the penis. Moreover, cause irreversible erectile dysfunction.
Interactions
People taking protease inhibitors for the treatment of HIV infection are advised to take only a 25 mg dose every 48 hours. Sildenafil citrate or viagra pill interferes with other drugs. Also, it can cause prolonged plasma half-life levels.
Contraindications
Contraindications include Associated use of nitric oxide donors, organic nitrates, and nitrates, such as:
- Nitroglycerin
- Isosorbide Mononitrate
- Isosorbide Dinitrate
- Sodium Nitroprusside
- Alkyl Nitrites
- Known hypersensitivity to sildenafil citrate.
Viagra- non-medical uses
Recreational use
The popularity of sildenafil citrate among young adults has increased over the years.
It is popular because young adults assume that it increases libido. Moreover improves sexual performance and enlarges the penis.
There are some limited studies about the recreational usage of sildenafil citrate. It shows a little effect on the men who do not have erectile dysfunction in men.
A 25 mg dose does not show a significant change in erectile quality. But it shortens the refractory time after ejaculation.
Sildenafil citrate and other PDE5 preventers are known for their illegal uses. This medication is abusive in nature.
That is why it is a controlled drug and requires a prescription to buy.
Jet lag research
The 2007 Nobel Prize in Aviation awarded to Patricia V. Agostino, Santiago A. Plano, and Diego A. Golombek of the National University of Quilmes, Argentina, for discovering that sildenafil citrate helps hamsters recover from jet lag.
Sports
Professional athletes believe that it increases the body’s blood flow. That helps them perform better. The sportsperson majorly takes Sildenafil.
Analogs
Acetildenafil and other synthetic structural analogs of sildenafil citrate prevent PDE5 found as adulterants in many “herbal” aphrodisiac products. These are available without a prescription.
These analogs have not undergone any of the rigorous testings. Drugs such as sildenafil citrate do have passed the test. Moreover, also have unknown side effect profiles.
Many attempts were earlier made to ban the drug, but it shows no result yet, or the progress has been slow.
Because of its abusive properties, the change is seen in its selling. Later decided that it can only sell with a prescription.
The US FDA has banned a variety of products called Eurycoma longifolia. As these actually contain only sildenafil citrate. The herbal products often only turn the sellers of this fake name into a product.
Detection in biological fluids
N-desmethyl and Sildenafil’s primary active metabolite is quantitating in plasma, serum, or whole blood, to assess the pharmacokinetic status in those receiving the drug for therapeutic purposes. Moreover, to confirm the diagnosis in potential poisoning victims. That helps to assist in treatment & forensic investigation in a fatal overdose.
Dosage of Viagra
Usually, the primary dose of viagra is 50 mg. Your healthcare provider will determine the best amount of Viagra for you. It will be base on your medical history and the medications. Also, on other supplements you are taking. Do not use Viagra daily.
The duration of Viagra depends on the person. For example, some men claim that this effect can last up to 5 hours, and the average product can last 30 to 120 minutes. Clinical studies have shown that taking 50 mg of Viagra is effective within 1-4 hours after taking it.
This study shows that administering sildenafil citrate at 150 to 200 mg doses results in insufficient stiffness, which is enough to achieve vaginal penetration and complete and satisfactory intercourse. Based on results among24.1% of patients with erectile dysfunction. Also, they had failed the sildenafil 100 mg test.
On Daily Basis
It may be safe to take Viagra daily if your healthcare is sounded good. In addition, if your medical history and current medications are not in conflict. Viagra has a short period of effectiveness. Using it may or may not be convenient for you, depending on several factors, including how often you have sex.
With another drug
Do not use Sildenafil if you are taking or have recently used riociguat (Adempas) or nitrates (medicines for chest pain), such as isosorbide dinitrate (Isordil), isosorbide mononitrate (Monoket), and nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat ).
History of Viagra
Viagra pill is a brand name for sildenafil citrate. A group of pharmaceutical chemists is developing it. They worked at Pfizer’s Sandwich, Kent, a research center in England.
Its first use being developed was to treat high blood pressure and ischemic heart disease.
Morriston Hospital in Swansea was the hospital for its first trials, which Ian Osterloh led. He suggested that the drug had little effect on angina pectoris. But it can also cause penis erections.
That’s when Pfizer decided to market it for erectile dysfunction instead of angina pectoris. The medicine was licensed in 1996.
But it got authorized for use in erectile dysfunction by the FDA on March 27, 1998. they were making it the first oral treatment approved for Erectile dysfunction (ED) in the United States.
It quickly became a huge success. Pfizer’s annual sales recorded in 2008 was $ 1.934 billion.
Recently Asked Questions About Viagra Pill
What should one know about the Viagra pill?
Viagra has been found safe and effective since it was approved by Pfizer and the FDA in the 1990s. But Viagra and other erectile dysfunction drugs are still prescription drugs. Hence you should consult a doctor before using them.
How long does it take for the Viagra pill to peak?
Since the concentration of Viagra in the blood peaks 60 minutes after taking the drug, the effects are most valuable at the current time. Thus, it is best to take Viagra about 1 hour before any sexual activity. It is possible to take Viagra with or without food.
Who shouldn’t take Viagra pill?
Men whose vital sign isn’t in check and people who take alpha-blockers (for high essential sign or prostate problems) shouldn’t take Viagra.
Also, you’ll not be ready to take these drugs if you take nitrate drugs (for chest pain) or had an attack or stroke within the past six months.
How does the Viagra pill make you feel?
Some men feel light-headed or dizzy. In rare cases, Viagra can cause fainting. Some men who are taking PDE5 preventers report back or muscle pain.
The main action of sildenafil citrate is to enhance the effect of nitric oxide (NO) by inhibiting the specific PDE-5 of cGMP. NO inside nasal mucosa handles vasodilation, leading to nasal congestion and obstruction.
What is the age limit for taking Viagra pills?
Viagra is a prescription drug approved for the treatment of erectile dysfunction (ED). You cannot get or keep an erection in erectile dysfunction. Viagra approved for its use in men over the age of 18.
What fruit is a natural Viagra pill?
Watermelon is a natural Viagra, says the researcher, as watermelon is more affluent in an amino acid called citrulline, which relaxes and dilates blood vessels much the same way as Viagra and other medications intended to treat erectile dysfunction (ED).
Will Viagra pill make you bigger?
If you have erectile dysfunction and it is ordinarily difficult for you to get a full erection, Viagra may make your erection feel more prominent than usual. Even so, it won’t physically make your penis more evident than its average size.
What can replace the Viagra pill?
Some alternative medications for erectile dysfunction (ED)
- First, Consuming Tadalafil Cialis tablet effect in just about an hour.
- Second, Vardenafil (Levitra) has to be taken an hour before sexual activity.
- Also, Vardenafil (Staxyn)
- Finally, Avanafil (Stendra)
How can I get hard fast without pills?
Eat more fruits, vegetables, whole grains, and legumes. The nutrients in many fruits, vegetables, whole grains, and legumes help improve blood flow throughout the body, including the penis. And blood flow to the penis is one of the keys to achieving healthy, consistent erections.
Can Viagra pill upset your stomach?
A fairly common side effect of Viagra is indigestion or an upset stomach. PDE5 inhibitors can sometimes cause nausea or vomiting.
What happens if a kid takes a Viagra pill?
Taking sildenafil citrate in children may cause mild symptoms, including persistent redness and engorgement of the penis with accompanying pain. The pain in the penis can persist even after the erection has disappeared.
How do you know when the Viagra pill is working?
Viagra usually starts to work as an oral tablet 30 to 60 minutes after taking it. It may take effect in two hours. Viagra doesn’t work alone.
Does Viagra pill make you last longer?
Viagra does not directly help you last longer in bed(unless you often lose your erection during sex); it’s still worth considering if you’re sensitive to male erecticle dysfunction.
Is Viagra pill terrible for your heart?
Even when a person isn’t taking nitrates, there’s been concern that Viagra might make his underlying heart condition much worse.
What happens after taking the Viagra pill?
When Viagra pill enters the body, it works by relaxing the walls of blood vessels and allows blood to flow more easily into the parts of the penis that cause construction.
What to expect when taking Viagra pill for the first time?
You will usually experience flushing, stomach pain or indigestion, or headaches. If you have a mild reaction to any side effect of Viagra, you may also want to see your doctor see if a lower dose might work better for you.
How much Viagra pill should I take for fun?
Use viagra pill only once a day. The usual recommended dose is 50 mg (range 25 mg to 100 mg), taken as needed, one hour before sexual activity.
Men can use between 30 minutes and four hours before sexual activity. Do not exceed the largest recommended dose.
What happens if you drink alcohol with a Viagra pill?
Some side effects of mixing Viagra pill and alcohol may include:
- Priapism (inability to maintain an erection), a painful, long-term erection, sudden hearing loss, sudden vision loss.
Is Viagra pill terrible for your health?
Taking Viagra pill can pose serious risks if you have an underlying medical condition. For example, men with heart disease who are taking drugs known as nitrates can develop dangerously low blood pressure when taking Viagra.
Most Asked Questions About Viagra
How long can the average man stay erect?
An erection can last from 5 to 30 minutes. On average, men can erect five times a night while they sleep, each lasting 25 to 35 minutes.
What alcohol makes you last longer in bed?
Drinking can give rise to distinct improvements within the sexual experience for males:
- Delayed ejaculation
- Enhanced libido and more intense erections
- Increased sexual stamina
What foods help you get hard?
Foods to Help Erectile Dysfunction
- Watermelons
- Oysters
- Dark Chocolate
- Nuts
- Juice
- Garlic
- Fish
- Green leafy vegetables
- Peppers
- Olive oil
What happens if you take Viagra without erectile dysfunction?
It wouldn’t be long for someone without erectile dysfunction to take Viagra, although you may think they feel better psychologically. But it would make a difference if you took it with other medications. Cocaine, marijuana, ecstasy, alcohol, nicotine, methamphetamine can all cause erection problems.
Does water help you last longer in bed?
Many factors can affect erectile dysfunction, including hydration levels. Drinking water can help maintain an erection because dehydration can reduce blood volume, affecting mood and erection. Erectile dysfunction is when a man has complications in achieving or maintaining an erection.
At what age does one have trouble getting hard?
About 5 percent of men in their 40s have complete erectile dysfunction, and that number increases to about 15 percent of men in their 70s. Mild and moderate erectile dysfunction affects about 10 percent of men per decade of their lives (50 percent of 50-year-old men, 60 percent of 60-year-old men).
Can you take Viagra with food?
Taking Viagra pill 1 hour before intercourse on an empty stomach or 2 hours after a meal to avoid delay ineffectiveness can be useful. You can take Viagra with a glass of water, or you can take it with milk or a light snack. Be aware that Viagra with whole milk or food can affect its effectiveness.
Does five-year-old Viagra work?
Viagra pills can continue to work for years after they are first manufactured. But the reduction in chemical activity means it won’t work as well. Expired medications can also grow fungi or infectious bacteria. Generally, Viagra and other drugs have a shelf life of about two years.
Does Viagra Help You Sleep?
The results showed that a single dose of Viagra significantly increased sleep time with lower oxygen saturation in the blood. Mean blood oxygen saturation was also lower after taking Viagra versus placebo.
Does viagra work faster if crushed?
Chewing Viagra does not make it work any faster. This is because the tablets you swallow or chew still need to be broken down in your digestive tract and go through a few more steps before they work.
What happens if a female takes Viagra?
About 42% of the women taking Viagra reported greater satisfaction during foreplay and intercourse than 28% of the women taking the placebo. Likewise, 57% of the women treated with Viagra reported a better feeling in the genital area during intercourse than 44% of the women taking the placebo.
Does caffeine affect Viagra?
Besides, caffeine significantly impacts the cardiovascular system by increasing heart rate and blood pressure resulting in increased cardiac output.
Thus, blood flow to the liver and sildenafil metabolism may increase in the presence of caffeine. Due to this, we observe increased blood flow.
Is viagra safe for 80-year-olds?
The most common adverse reactions were flushing and dyspepsia, which occurred in 6.8% and 2.3%, respectively. No patient discontinued Sildenafil because of side effects. In conclusion, oral Sildenafil is effective and well-tolerated by older men with ED, even those over 70 years old.
Does viagra lower blood pressure?
This has shown that Sildenafil causes an average reduction in blood pressure even when taken in conjunction with other antihypertensive drugs, providing peace of mind about its safety when taken as a single dose for erectile dysfunction.
Does Viagra lose effectiveness?
The ingredients in Viagra break down over time likewise other medications. This means that the drug’s effects will be much less powerful each day after it expires.
Can I take Viagra with milk?
You can take a Viagra pill with a glass of water, or you can take it with milk or a light snack. Be aware that Viagra with whole milk or food can affect its effectiveness. Always talk to your doctor or pharmacist about the best way to take Viagra, even if there are foods or drinks that you should avoid.
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